Roosevelt jumped out to a ten-point advantage in the first quarter before Lincoln rallied in the second quarter, outscoring the Roughriders 14-7 in the second quarter to go into halftime trailing 23-21.
The Railsplitters took control of the game in the third quarter, outscoring Roosevelt 17-6 in the third quarter to take a 38-29 lead. Roosevelt rallied to cut into Des Moines Lincoln's lead in the fourth quarter only to fall short.
Chelleen led all scorers with 18 points with seven rebounds while Amy Nichol added 14 points while Rachel Mitchell and Laechia Conley added 11 points apiece.
Charmaine Bell and Tanyana West paced Roosevelt with 13 points apiece.
Des Moines Lincoln will face Cedar Rapids Kennedy or Dowling Catholic at 2:30 p.m. Friday in the Class 4A semifinals.
Des Moines Roosevelt ends its season at 15-8.
Des Moines Roosevelt (15-8) 16 7 6 23 -- 53
Des Moines Lincoln (23-1) 7 14 17 17 -- 55